very late effects of postoperative atrial fibrillation on outcome of coronary artery bypass graft surgery

Authors

majid haghjoo cardiac electrophysiology research center, rajaie cardiovascular medical and research center, tehran university of medical sciences, tehran, ir iran; cardiac electrophysiology research center, rajaie cardiovascular medical center, mellat park, vali-e-asr avenue, tehran, ir iran. p.o.box: 15745-1341. tel: +98-212392 2163, fax: +98- 212204 8174

mona heidarali cardiac electrophysiology research center, rajaie cardiovascular medical and research center, tehran university of medical sciences, tehran, ir iran

salman nikfarjam cardiac electrophysiology research center, rajaie cardiovascular medical and research center, tehran university of medical sciences, tehran, ir iran

mohammadmahdi peighambari cardiovascular intervention research center, rajaie cardiovascular medical and research center, tehran university of medical sciences, tehran, ir iran

abstract

background: atrial fibrillation (af) after coronary artery bypass graft (cabg) is a common complication with potentially higher risk of adverse outcome and prolonged hospital stay. objective: to determine the impact of postoperative af (poaf) on long-term outcome in a large cohort of patients who underwent cabg. patients and methods: we conducted an observational cohort study of 989 patients who underwent isolated cabg with more than 5-year follow-up. patient divided in two groups: patients with and without poaf. results: in this study, atrial fibrillation developed after cabg in 156 patients (15.8%). patients with poaf were generally older (p = 0.001) and presented more often with comorbidities including congestive heart failure (p = 0.001), hypertension (p = 0.001), peripheral vascular disease (p = 0.001), hyperlipidemia (p = 0.009), and renal failure (p = 0.001). five-year mortality was observed in 23 (2.3%) patients. patients with poaf had higher five-year mortality rate than those without poaf. multivariate logistic analysis showed that af after surgery has a strong effect on mortality (hr, 3.3; 95% ci, 0.04-10.8, p = 0.04) and morbidity rates (hr, 4.0; 95% ci, 2.35-6.96, p = 0.001). conclusions: postoperative atrial fibrillation strongly predicts higher long-term mortality and morbidity following coronary artery bypass graft.

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Journal title:
research in cardiovascular medicine

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